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Creamy Cajun Chicken and Rotini

Creamy Cajun Chicken and Rotini

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Creamy Cajun Chicken and Rotini is a comforting and satisfying dish that brings together tender chicken, spiraled rotini pasta, and a rich, cheesy sauce inspired by bold Cajun flavors. Perfect for busy weeknights or special gatherings, this creamy pasta recipe is sure to impress both family and friends. The delightful combination of spices and cheeses creates a memorable dining experience that will have everyone asking for more. Not only is it quick to prepare, but it’s also easily customizable with your favorite vegetables or proteins, making it a versatile addition to your mealtime repertoire.

  • Total Time: 35 minutes
  • Yield: Serves 4

Ingredients

Scale
  • 1 lb boneless, skinless chicken breasts, cut into thick strips
  • 12 oz rotini pasta
  • 1 cup heavy cream
  • 1 cup shredded mozzarella cheese
  • 1 cup cubed Velveeta cheese
  • 1 cup grated Parmesan cheese
  • 1 tablespoon Cajun seasoning
  • 1 teaspoon garlic powder
  • 1 teaspoon onion powder
  • 2 tablespoons olive oil
  • 3 tablespoons unsalted butter, divided
  • 3 cloves garlic, minced
  • Salt and black pepper, to taste
  • Reserved pasta water (if needed)
  • 1 tablespoon chopped parsley (optional)

Instructions

  1. Season the chicken strips with Cajun seasoning, garlic powder, onion powder, salt, and pepper. Toss to coat evenly.
  2. In a large skillet over medium-high heat, add olive oil and 2 tablespoons of butter. Once hot, sear the chicken until golden-brown and fully cooked, about 4-5 minutes per side. Transfer to a plate and keep warm.
  3. Bring a large pot of salted water to a boil and cook the rotini until al dente. Reserve ½ cup of pasta water, then drain and set aside.
  4. In the same skillet, lower the heat and melt the remaining tablespoon of butter. Add minced garlic and sauté for 30 seconds until fragrant.
  5. Pour in heavy cream and bring to a gentle simmer. Add Velveeta cubes and stir until melted and smooth.
  6. Stir in mozzarella and Parmesan cheeses and mix until the sauce is thick and creamy. Adjust consistency with reserved pasta water if needed.
  7. Add cooked rotini to the sauce and gently toss until all pasta is coated.
  8. Serve creamy rotini on one side of each plate with seared chicken on the other side. Garnish with chopped parsley if desired.
  • Author: Sarah DuRoss
  • Prep Time: 10 minutes
  • Cook Time: 25 minutes
  • Category: Main
  • Method: Stovetop
  • Cuisine: Cajun

Nutrition

  • Serving Size: 1 plate (approximately 320g)
  • Calories: 620
  • Sugar: 4g
  • Sodium: 780mg
  • Fat: 36g
  • Saturated Fat: 21g
  • Unsaturated Fat: 13g
  • Trans Fat: 0g
  • Carbohydrates: 59g
  • Fiber: 3g
  • Protein: 30g
  • Cholesterol: 115mg