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Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce

Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce

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Indulge in the rich and creamy delight of Garlic Parmesan Chicken Penne in Creamy Cajun Three-Cheese Sauce. This comforting pasta dish brings together tender chicken, a medley of three cheeses, and zesty Cajun seasoning for a flavor experience that’s simply irresistible. Perfect for busy weeknights or special gatherings, it can be prepared in just 30 minutes with minimal cleanup required. The combination of savory garlic and cheesy goodness creates a meal that appeals to both kids and adults alike. Serve it alongside a fresh salad or garlic bread for an unforgettable dining experience.

  • Total Time: 30 minutes
  • Yield: Serves approximately 4 people 1x

Ingredients

Scale
  • 1 lb boneless, skinless chicken breasts
  • 12 oz penne pasta
  • 4 cloves garlic
  • 1 ½ cups heavy cream
  • ½ cup chicken broth
  • ½ cup shredded mozzarella cheese
  • ½ cup shredded cheddar cheese
  • ½ cup grated Parmesan cheese
  • 2 tablespoons olive oil
  • 3 tablespoons unsalted butter
  • 1 tablespoon Cajun seasoning
  • Salt and freshly ground black pepper to taste

Instructions

  1. Cook penne pasta according to package instructions until al dente; drain.
  2. Season chicken pieces with Cajun seasoning, salt, and pepper.
  3. In a large skillet over medium-high heat, heat olive oil and cook chicken until golden (about 6-8 minutes). Remove and set aside.
  4. In the same skillet, melt butter over medium heat; sauté minced garlic for 1-2 minutes until fragrant.
  5. Stir in heavy cream and chicken broth; bring to a gentle simmer.
  6. Add mozzarella, cheddar, and Parmesan cheeses; stir until melted and smooth.
  7. Return cooked chicken to the skillet; toss to coat with sauce.
  8. Add cooked penne pasta; mix until fully coated with sauce.
  9. Garnish with chopped parsley before serving.
  • Author: Sarah DuRoss
  • Prep Time: 10 minutes
  • Cook Time: 20 minutes
  • Category: Dinner
  • Method: Skillet
  • Cuisine: American

Nutrition

  • Serving Size: 1 cup (250g)
  • Calories: 685
  • Sugar: 3g
  • Sodium: 820mg
  • Fat: 43g
  • Saturated Fat: 23g
  • Unsaturated Fat: 18g
  • Trans Fat: 0g
  • Carbohydrates: 42g
  • Fiber: 2g
  • Protein: 37g
  • Cholesterol: 140mg